In combination with a Phe-restricted diet, prescription PKU medications are available, which may help reduce blood Phe levels.
References 1. Vockley J, Andersson HC, Antshel KM, et al; American College of Medical Genetics and Genomics Therapeutic Committee. Phenylalanine hydroxylase deficiency: diagnosis and management guidelines. Genet Med. 2014;16(2):188-200.