Description
Trautwein et al. aimed to expand upon the achondroplasia foramen magnum score (AFMS) system to identify anatomical characteristics in children with achondroplasia to allow for the development of a standardised indication for decompression surgery and a standardised evaluation of the effect of medical treatment on critical intracranial structures. Findings from scans reviewed during this study offer an opportunity to develop a tool to assist with the indication of decompression surgery and aid in measuring the outcome following treatment with precision therapies.
The cohort for this study included 37 children with achondroplasia, and a reference population of 37 children without achondroplasia. 12 parameters were measured and AFMS was calculated for the achondroplastic group. Significant differences were found between the achondroplastic and reference groups in 10 of the parameters measured, and AFMS was retrospectively determined in 24 of the 37 children with achondroplasia.
