Description

The short stature, shortened limbs, and medical complications typical of ACH substantially impact both physical and psychosocial aspects of daily life from a very early age. Although clinical features and medical complications have been well described, functional and psychosocial aspects have received less attention.

This study reviewed the literature on physical functioning, psychosocial function, and QoL in ACH compared to average stature or other short stature conditions. Data from 23 studies were included, and show that people with ACH face physical, social, and emotional challenges on a daily basis. However, despite the life-long complications, many patients are able to adapt functionally and psychologically. More research is needed to understand the impact of disproportionate short stature, as well as to assess the effects of limb lengthening and other treatments.

Access via PubMed

EU-ACH-00342