{"id":69,"date":"2022-11-28T20:56:42","date_gmt":"2022-11-28T20:56:42","guid":{"rendered":"https:\/\/hcp.biomarin.com\/en-us\/voxzogo2\/?page_id=69"},"modified":"2024-09-09T21:34:10","modified_gmt":"2024-09-09T21:34:10","slug":"dosing-calculator","status":"publish","type":"page","link":"https:\/\/hcp.biomarin.com\/en-us\/voxzogo\/dosing-calculator\/","title":{"rendered":"VOXZOGO Dosing Calculator"},"content":{"rendered":"<div id=\"acf-block-6645d55c30cc6\" class=\"block wrapped-content block-tight-top\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-6645d55c30e03\" class=\"block-wysiwyg\">\n            <h1>The volume of VOXZOGO administered is based on patients\u2019 actual body weight.<sup>1<\/sup><\/h1>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-63f535558b78a\" class=\"block dosage-calculator block-tight-top block-tight-bottom\">\n    <div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\">\n\t\t\t                        <div class=\"dosage-calculator-intro\">\n                                                                            <p>This dosing calculator can help you determine the appropriate dose based on your patients\u2019 body weight and the concentration of reconstituted VOXZOGO.<\/p>\n                                            <\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"dosage-calculator-calculation\">\n\t\t\t\t\t<div class=\"dosage-calculator-input\">\n\t\t\t\t\t\t<div class=\"form-item\">\n\t\t\t\t\t\t\t<label for=\"dosage-calcuator-weight\">Patient&rsquo;s Weight (kg)<\/label>\n\t\t\t\t\t\t\t<select class=\"text\" id=\"dosage-calculator-weight\" name=\"dosage-calculator-weight\">\n\t\t\t\t\t\t\t\t<option value=\"select\">Select<\/option>\n\t\t\t\t\t\t\t\t<option value=\"3kg\">3 kg<\/option>\n\t\t\t\t\t\t\t\t<option value=\"4kg\">4 kg<\/option>\n\t\t\t\t\t\t\t\t<option value=\"5kg\">5 kg<\/option>\n\t\t\t\t\t\t\t\t<option value=\"6_7kg\">6-7 kg<\/option>\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<option value=\"8_11kg\">8-11 kg<\/option>\n\t\t\t\t\t\t\t\t<option value=\"12_16kg\">12-16 kg<\/option>\n\t\t\t\t\t\t\t\t<option value=\"17_21kg\">17-21 kg<\/option>\n\t\t\t\t\t\t\t\t<option value=\"22_32kg\">22-32 kg<\/option>\n\t\t\t\t\t\t\t\t<option value=\"33_43kg\">33-43 kg<\/option>\n\t\t\t\t\t\t\t\t<option value=\"44_59kg\">44-59 kg<\/option>\n\t\t\t\t\t\t\t\t<option value=\"60_89kg\">60-89 kg<\/option>\n\t\t\t\t\t\t\t\t<option value=\"\u226590kg\">\u226590 kg<\/option>\n\t\t\t\t\t\t\t<\/select>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"dosage-calculator-output\">\n\n\t\t\t\t\t\t<div class=\"dosage-calculator-output-header\">\n\t\t\t\t\t\t\t<h3>Details about your patient&rsquo;s recommended dose<\/h3>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<div class=\"dosage-calcuator-result-row\">\n\t\t\t\t\t\t\t<h4>Check:<\/h4>\n\t\t\t\t\t\t\t<div class=\"dosage-calculator-result\">\n\t\t\t\t\t\t\t\t<p>Recommended vial strength for reconstitution should show <span class=\"dynamic-value\"><span class=\"result result-strength\"><\/span> mg<\/span> on the label.<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<div class=\"dosage-calcuator-result-row\">\n\t\t\t\t\t\t\t<h4>Check:<\/h4>\n\t\t\t\t\t\t\t<div class=\"dosage-calculator-result check\">\n\t\t\t\t\t\t\t\t<p>Vial should have a <span class=\"vial-colour vial-colour-white\">white<\/span>, <span class=\"vial-colour vial-colour-magenta\">magenta<\/span>, or <span class=\"vial-colour vial-colour-gray\">gray<\/span> colored cap.<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<div class=\"dosage-calcuator-result-row\">\n\t\t\t\t\t\t\t<h4>Inject:<\/h4>\n\t\t\t\t\t\t\t<div class=\"dosage-calculator-result\">\n\t\t\t\t\t\t\t\t<p>After reconstitution, <span class=\"dynamic-value\"><span class=\"result result-dose\"><\/span> mL<\/span> should be injected.<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\n\t\t\t\t<table class=\"dosage-data\">\n\t\t\t\t\t<thead>\n\t\t\t\t\t\t<tr>\n\t\t\t\t\t\t\t<th>Body Weight<\/th>\n\t\t\t\t\t\t\t<th>Vial Strength for Reconstitution*<\/th>\n\t\t\t\t\t\t\t<th>Dose<\/th>\n\t\t\t\t\t\t\t<th>Injection Volume<\/th>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t<\/thead>\n\t\t\t\t\t<tbody>\n\t\t\t\t\t\t<tr class=\"white\">\n\t\t\t\t\t\t\t<td>3 kg<\/td>\n\t\t\t\t\t\t\t<td rowspan=\"5\">0.4 mg<\/td>\n\t\t\t\t\t\t\t<td>0.096 mg<\/td>\n\t\t\t\t\t\t\t<td>0.12 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"white\">\n\t\t\t\t\t\t\t<td>4 kg<\/td>\n\t\t\t\t\t\t\t<td>0.12 mg<\/td>\n\t\t\t\t\t\t\t<td>0.15 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"white\">\n\t\t\t\t\t\t\t<td>5 kg<\/td>\n\t\t\t\t\t\t\t<td>0.16 mg<\/td>\n\t\t\t\t\t\t\t<td>0.2 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"white\">\n\t\t\t\t\t\t\t<td>6-7 kg<\/td>\n\t\t\t\t\t\t\t<td>0.2 mg<\/td>\n\t\t\t\t\t\t\t<td>0.25 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"white\">\n\t\t\t\t\t\t\t<td>8-11 kg<\/td>\n\t\t\t\t\t\t\t<td>0.24 mg<\/td>\n\t\t\t\t\t\t\t<td>0.3 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"magenta\">\n\t\t\t\t\t\t\t<td>12-16 kg<\/td>\n\t\t\t\t\t\t\t<td rowspan=\"3\">0.56 mg<\/td>\n\t\t\t\t\t\t\t<td>0.28 mg<\/td>\n\t\t\t\t\t\t\t<td>0.35 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"magenta\">\n\t\t\t\t\t\t\t<td>17-21 kg<\/td>\n\t\t\t\t\t\t\t<td>0.32 mg<\/td>\n\t\t\t\t\t\t\t<td>0.40 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"magenta\">\n\t\t\t\t\t\t\t<td>22-32 kg<\/td>\n\t\t\t\t\t\t\t<td>0.40 mg<\/td>\n\t\t\t\t\t\t\t<td>0.50 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"gray\">\n\t\t\t\t\t\t\t<td>33-43 kg<\/td>\n\t\t\t\t\t\t\t<td rowspan=\"4\">1.2 mg<\/td>\n\t\t\t\t\t\t\t<td>0.50 mg<\/td>\n\t\t\t\t\t\t\t<td>0.25 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"gray\">\n\t\t\t\t\t\t\t<td>44-59 kg<\/td>\n\t\t\t\t\t\t\t<td>0.60 mg<\/td>\n\t\t\t\t\t\t\t<td>0.30 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"gray\">\n\t\t\t\t\t\t\t<td>60-89 kg<\/td>\n\t\t\t\t\t\t\t<td>0.70 mg<\/td>\n\t\t\t\t\t\t\t<td>0.35 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t\t<tr class=\"gray\">\n\t\t\t\t\t\t\t<td>\u2265 90 kg<\/td>\n\t\t\t\t\t\t\t<td>0.80 mg<\/td>\n\t\t\t\t\t\t\t<td>0.4 mL<\/td>\n\t\t\t\t\t\t<\/tr>\n\t\t\t\t\t<\/tbody>\n\t\t\t\t<\/table>\n\n                                    <p class=\"dosage-data-footnote\">\n                        *Intermediate body weights that fall within these weight bands should be rounded to the nearest whole number.<br \/>\n<sup>\u2020<\/sup>The concentration of vosoritide in reconstituted 0.4 mg vial and 0.56 mg vial is 0.8 mg\/mL. The concentration of vosoritide in reconstituted 1.2 mg vial is 2 mg\/mL.\n                    <\/p>\n\t\t\t\t\n                                    <div class=\"dosage-calculator-disclaimer\">\n                        <h3>Disclaimer<\/h3>\n<p>By using this resource, you agree to the following: This Dosing Calculator is being provided as is and is intended for use only by qualified healthcare providers. All calculations should be confirmed before use. BioMarin Pharmaceutical Inc. makes no claims as to the accuracy of the information contained herein. This calculator does not replace the need for independent clinical judgment. Neither BioMarin Pharmaceutical Inc., nor any other party involved in the preparation of this site, shall be liable to you or others for any decisions made or action taken by you or others in reliance on this information.<\/p>\n<p>Please also refer to the <a href=\"https:\/\/d34r3hkxgxjdtw.cloudfront.net\/6f836309-d95f-42af-b717-2efa058ad82d\/1356eb37-6270-4c81-877a-83f0a4df7271\/1356eb37-6270-4c81-877a-83f0a4df7271_source__v.pdf\" target=\"_blank\" rel=\"noopener\">VOXZOGO Instructions for Use<\/a>.<\/p>\n                    <\/div>\n                \t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-6645d1fdce094\" class=\"block cards cards-3-col block-zero-bottom\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"cards-title\">\n\t\t\t    \t\t\t\t\t\t\t\t    <h2>Regularly follow up every 3 to 6 months to assess weight and linear growth<sup>1<\/sup><\/h2>\n<p>Body weight affects VOXZOGO clearance and volume of distribution. When treating with VOXZOGO, it\u2019s important to monitor growth every 3 to 6 months, including:<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"cards-wrapper\">\n\t\t\t    \n<div id=\"acf-block-6645d1fdce66b\" class=\"card card-centered card-inner-image card-inner-image-medium\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/hcp.biomarin.com\/en-us\/voxzogo\/wp-content\/uploads\/sites\/4\/2024\/06\/icon-height.png?v=0.120\" alt=\"Height\" \/>                \n                                                                                                            <h3>Height<\/h3>\n                                                                                    <\/div>\n<\/div>\n\n<div id=\"acf-block-6645d1fdce6e5\" class=\"card card-centered card-inner-image card-inner-image-medium\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/hcp.biomarin.com\/en-us\/voxzogo\/wp-content\/uploads\/sites\/4\/2024\/06\/icon-weight.png?v=0.120\" alt=\"Weight\" \/>                \n                                                                                                            <h3>Body weight<\/h3>\n                                                                                    <\/div>\n<\/div>\n\n<div id=\"acf-block-6645d1fdce748\" class=\"card card-centered card-inner-image card-inner-image-medium\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/hcp.biomarin.com\/en-us\/voxzogo\/wp-content\/uploads\/sites\/4\/2024\/06\/icon-development.png?v=0.120\" alt=\"Development\" \/>                \n                                                                                                            <h3>Physical development<\/h3>\n                                                                                    <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-63f535558b7f5\" class=\"block references block-zero-bottom\">\n    <div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t    \t\t\t    <h4>Reference:\n<\/h4>\n\t\t\t\t\t\t                <ol>\n                                                                                                                        <li><span>VOXZOGO [package insert]. Novato, CA: BioMarin Pharmaceutical Inc; 2023.\n<\/span><\/li>\n                                                            <\/ol>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Dosing Calculator | VOXZOGO\u00ae (vosoritide) HCP<\/title>\n<meta name=\"description\" content=\"The VOXZOGO dosing calculator can help you determine the appropriate dose based on your patients\u2019 body weight and the concentration of reconstituted VOXZOGO\u00ae.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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