{"id":3308,"date":"2025-10-29T12:16:21","date_gmt":"2025-10-29T12:16:21","guid":{"rendered":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/?page_id=3308"},"modified":"2025-12-15T13:13:38","modified_gmt":"2025-12-15T13:13:38","slug":"referring-patients","status":"publish","type":"page","link":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/referring-patients\/","title":{"rendered":"Referring patients"},"content":{"rendered":"<div id=\"acf-block-69121e24777d7\" class=\"hero hero-roctavian\">\n    <div class=\"hero-background-image hero-background-image-desktop\" style=\"background-image: url(https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-content\/uploads\/sites\/3\/2025\/11\/lorenzo-scaled-e1763381215132.png?v=1.49);\"><\/div>\n    <div class=\"hero-background-image hero-background-image-mobile\" style=\"background-image: url(https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-content\/uploads\/sites\/3\/2025\/11\/HCP_3.0-REFERING-PATIENTS_MOBILE.png?v=1.49);\"><\/div>\n    <div class=\"overlay\"><\/div>\n\n    <div class=\"hero-content\">\n        <div class=\"title-area\">\n                            <h1>HOW TO REFER PATIENTS\n<\/h1>\n                                <\/div>\t\t\n                    <div class=\"text-area\">\n                <div class=\"text-area-content\">\n                                        <div class=\"text\">\n                        <p>Help patients find a prescribing hemophilia treatment center (HTC)<\/p>\n                    <\/div>\n                                                                <div class=\"cta\">\n                                                                                    <p><a class=\"button\" href=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/find-a-hemophilia-treatment-center\/\" target=\"_self\">Find a HTC<\/a><\/p>\n                        <\/div>\n                                    <\/div>\n            <\/div>\n                            <div class=\"image-caption\">\n                <p class=\"p1\">Lorenzo V., dosed with ROCTAVIAN in 2019 as part of a clinical trial.<\/p>\n            <\/div>\n\n            <div class=\"additional-caption\">\n                            <\/div>\n            <\/div>\n<\/div>\n\n\n<div id=\"acf-block-69020f65bdd89\" class=\"block wrapped-content\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-69020f65bded7\" class=\"block-wysiwyg\">\n            <h2>Referring patients to a dosing HTC<\/h2>\n<p>ROCTAVIAN has been administered in HTCs nationwide. Follow these simple steps to help eligible patients get started with one.<\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69020f65be097\" class=\"block boxed-content top-border block-zero-bottom boxed-content-white\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\">\n\t\t\t\t\t\t\t\t\n<div id=\"acf-block-69020f65be367\" class=\"image-text-block\">\n            <div class=\"image-block small\">\n            <figure>\n                <div class=\"image image-rounded\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-content\/uploads\/sites\/3\/2023\/05\/4.1_Step-1-icon.png?v=1.49\" alt=\"Step 1\" \/>                <\/div>\n            <\/figure>\n        <\/div>\n        <div class=\"content-block\">\n                    <p style=\"color: #571e4c\"><strong>Eligibility diagnostics<\/strong><\/p>\n                            <ul>\n<li>The home HTC and dosing HTC should coordinate to determine which site will order the eligibility diagnostics\n<ul>\n<li>Your BioMarin Account Manager and Therapy Access Manager can help you understand the<br \/>\neligibility process<\/li>\n<\/ul>\n<\/li>\n<li>Determine which site will receive the eligibility diagnostic results and which will notify the patient of their eligibility status<\/li>\n<li>Determine which site will reiterate lifestyle and safety considerations of ROCTAVIAN with patients<\/li>\n<\/ul>\n                    <\/div>\n<\/div>\n\n<div id=\"acf-block-69020f65be3f7\" class=\"image-text-block\">\n            <div class=\"image-block small\">\n            <figure>\n                <div class=\"image image-rounded\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-content\/uploads\/sites\/3\/2023\/05\/4.1_Step-2-icon.png?v=1.49\" alt=\"Step 2\" \/>                <\/div>\n            <\/figure>\n        <\/div>\n        <div class=\"content-block\">\n                    <p style=\"color: #571e4c\"><strong>Securing patient coverage<\/strong><\/p>\n                            <ul>\n<li>Either the home HTC or the dosing HTC may secure coverage for the patient<\/li>\n<li>If the patient is being referred to a separate dosing HTC for the infusion, but the patient\u2019s home HTC is securing coverage, consider coordinating logistics with the dosing HTC<\/li>\n<\/ul>\n                    <\/div>\n<\/div>\n\n<div id=\"acf-block-69020f65be46a\" class=\"image-text-block\">\n            <div class=\"image-block small\">\n            <figure>\n                <div class=\"image image-rounded\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-content\/uploads\/sites\/3\/2023\/05\/4.1_Step-3-icon.png?v=1.49\" alt=\"Step 3\" \/>                <\/div>\n            <\/figure>\n        <\/div>\n        <div class=\"content-block\">\n                    <p style=\"color: #571e4c\"><strong>Patient coordination<\/strong><\/p>\n                            <ul>\n<li>Ensure that both HTCs are working together to coordinate the gene therapy infusion<\/li>\n<li>Determine which HTC will be responsible for post-infusion patient monitoring<\/li>\n<\/ul>\n                    <\/div>\n<\/div>\n\n<div id=\"acf-block-69020f65be4db\" class=\"image-text-block block-zero-bottom\">\n            <div class=\"image-block small\">\n            <figure>\n                <div class=\"image image-rounded\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-content\/uploads\/sites\/3\/2023\/05\/4.1_Step-4-icon.png?v=1.49\" alt=\"Step 4\" \/>                <\/div>\n            <\/figure>\n        <\/div>\n        <div class=\"content-block\">\n                    <p style=\"color: #571e4c\"><strong>Coordinate between HTCs<\/strong><\/p>\n                            <p>The home and dosing HTCs should work together to confirm:<\/p>\n<ul>\n<li>The dosing HTC is listed on the Health Resources and Services Administration website as a contract pharmacy for the home HTC<\/li>\n<li>Whether a contract between sites is needed<\/li>\n<li>The ship-to address is correct and reflects where the product will be delivered for the infusion<\/li>\n<li>The date and time of patient infusion<\/li>\n<li>If patient travel will be required. If so, the dosing HTC should coordinate with the patient<\/li>\n<\/ul>\n                    <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-69020f65be51a\" class=\"block wrapped-content block-zero-top\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<figure id=\"acf-block-691c89a424fb6\">\n    <div class=\"image image-rounded image-align-left\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-content\/uploads\/sites\/3\/2025\/11\/Screenshot-2025-11-04-at-13.50.06-e1763033622336.png?v=1.49\" alt=\"\" \/>            <\/div>\n    <\/figure>\n\n<div id=\"acf-block-69020f65be53b\" class=\"block-wysiwyg\">\n            <h5>Administration of ROCTAVIAN does not eliminate the ability to return to prophylaxis<sup>1<\/sup><\/h5>\n<p>In the clinical trial, some patients had increased Factor VIII activity levels but it was determined that they had not responded or lost response to ROCTAVIAN. These patients returned to prophylaxis.<\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69121f90c97c7\" class=\"block wrapped-content\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<figure id=\"acf-block-69121f90c99cf\">\n    <div class=\"image image-rounded image-natural-size image-align-center\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-content\/uploads\/sites\/3\/2025\/10\/3.0-REFERING_question-icon-e1762179972404.png?v=1.49\" alt=\"Two speech bubbles interacting in conversation\" \/>            <\/div>\n    <\/figure>\n\n<div id=\"acf-block-69121f90c9b09\" class=\"block-wysiwyg\">\n            <h2 style=\"text-align: center\">Questions?<\/h2>\n<h5 style=\"text-align: center;color:#1D3040\">Our team of experts is here to help<\/h5>\n<p style=\"text-align: center\"><a class=\"button\" href=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/connect-with-us\/\">Connect with Us<\/a><\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69121e2478571\" class=\"block single-stacked-video\" data-muted-autoplay=\"false\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            \n                            <h2 class=\"h3\">\u201cIt\u2019s possible to live a life with severe hemophilia A that may not include continuous prophylaxis.\u201d\n<\/h2>\n                                        <div class=\"supporting-text\">\n                    <p>\u2014Dave N., dosed with ROCTAVIAN in 2024<\/p>\n                <\/div>\n                        \n            <div class=\"video-poster\">\n                <a class=\"modal-video permitted\" href=\"https:\/\/player.vimeo.com\/video\/1136214532\" style=\"background-image: url(https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-content\/uploads\/sites\/3\/2025\/10\/3.0-REFERING_David-N_packing.png?v=1.49);\">Play<\/a>\n            <\/div>\n            \n                            <p><a class=\"button\" href=\"https:\/\/player.vimeo.com\/video\/1136214532\" target=\"_self\">Watch his story<\/a><\/p>            \n                    <\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-69020f65bf22d\" class=\"block call-to-action dark-cta\">\n    <div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\" style=\"\">\n\t\t\t\t<div class=\"overlay\"><\/div>\n\t\t\t\t<div class=\"cta-content\">\n\t\t\t\t    \t\t\t\t\t<div class=\"cta-content-main\">\n                        <div class=\"content-block\">\n\t\t\t\t\t        \t\t\t\t\t        \t\t\t\t\t\t        <h2 class=\"h3\">Want to hear from real patients who have chosen ROCTAVIAN?\n<\/h2>\n\t\t\t\t\t\t    \t\t\t\t\t\t    \t\t\t\t\t\t        <p>Discover their stories.<\/p>\n\t\t\t\t\t\t    \t\t\t\t\t    <\/div>\n\t\t\t\t\t                                <div class=\"content-block\">\n                                <p><a class=\"button button-ghost button-arrow\" href=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/patient-stories\/\" target=\"_self\">WATCH NOW<\/a><\/p>\n                            <\/div>\n\t\t\t\t\t                        <\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-3308","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Referring Patients | ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox) for Healthcare Professionals<\/title>\n<meta name=\"description\" content=\"Learn about referring eligible patients to a dosing HTC to receive treatment with ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox)\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/referring-patients\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Referring Patients | ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox) for Healthcare Professionals\" \/>\n<meta property=\"og:description\" content=\"Learn about referring eligible patients to a dosing HTC to receive treatment with ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox)\" \/>\n<meta property=\"og:url\" content=\"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/referring-patients\/\" \/>\n<meta property=\"og:site_name\" content=\"BioMarin Roctavian HCP EN-US\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-15T13:13:38+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/roctavian\\\/referring-patients\\\/\",\"url\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/roctavian\\\/referring-patients\\\/\",\"name\":\"Referring Patients | ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox) for Healthcare Professionals\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/roctavian\\\/#website\"},\"datePublished\":\"2025-10-29T12:16:21+00:00\",\"dateModified\":\"2025-12-15T13:13:38+00:00\",\"description\":\"Learn about referring eligible patients to a dosing HTC to receive treatment with ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox)\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/roctavian\\\/referring-patients\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/roctavian\\\/referring-patients\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/roctavian\\\/referring-patients\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/roctavian\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Referring patients\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/roctavian\\\/#website\",\"url\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/roctavian\\\/\",\"name\":\"BioMarin Roctavian HCP EN-US\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/roctavian\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Referring Patients | ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox) for Healthcare Professionals","description":"Learn about referring eligible patients to a dosing HTC to receive treatment with ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox)","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/referring-patients\/","og_locale":"en_US","og_type":"article","og_title":"Referring Patients | ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox) for Healthcare Professionals","og_description":"Learn about referring eligible patients to a dosing HTC to receive treatment with ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox)","og_url":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/referring-patients\/","og_site_name":"BioMarin Roctavian HCP EN-US","article_modified_time":"2025-12-15T13:13:38+00:00","twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/referring-patients\/","url":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/referring-patients\/","name":"Referring Patients | ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox) for Healthcare Professionals","isPartOf":{"@id":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/#website"},"datePublished":"2025-10-29T12:16:21+00:00","dateModified":"2025-12-15T13:13:38+00:00","description":"Learn about referring eligible patients to a dosing HTC to receive treatment with ROCTAVIAN\u00ae (valoctocogene roxaparvovec-rvox)","breadcrumb":{"@id":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/referring-patients\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/hcp.biomarin.com\/en-us\/roctavian\/referring-patients\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/referring-patients\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/"},{"@type":"ListItem","position":2,"name":"Referring patients"}]},{"@type":"WebSite","@id":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/#website","url":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/","name":"BioMarin Roctavian HCP EN-US","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-json\/wp\/v2\/pages\/3308","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-json\/wp\/v2\/comments?post=3308"}],"version-history":[{"count":23,"href":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-json\/wp\/v2\/pages\/3308\/revisions"}],"predecessor-version":[{"id":3810,"href":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-json\/wp\/v2\/pages\/3308\/revisions\/3810"}],"wp:attachment":[{"href":"https:\/\/hcp.biomarin.com\/en-us\/roctavian\/wp-json\/wp\/v2\/media?parent=3308"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}