{"id":7224,"date":"2025-06-17T13:01:57","date_gmt":"2025-06-17T13:01:57","guid":{"rendered":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/?page_id=7224"},"modified":"2025-11-17T19:32:34","modified_gmt":"2025-11-17T19:32:34","slug":"resources-rems","status":"publish","type":"page","link":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/","title":{"rendered":"PALYNZIQ REMs"},"content":{"rendered":"<div id=\"acf-block-68516acba761b\" class=\"wrapper hero-wrapper\">\n    <div class=\"hero hero-blue hero-wide-half\">\n                <div class=\"overlay\"><\/div>\n        <div class=\"wrapper\">\n            <div class=\"inner-wrapper\">\n                <div class=\"hero-content\">\n                                                                                    <h1>WHAT IS THE PALYNZIQ RISK EVALUATION AND MITIGATION STRATEGY <span>(REMS)<\/span>?\n<\/h1>\n                                                                                                <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n\n<div id=\"acf-block-68516acba783e\" class=\"block wrapped-content bg-band bg-band-primary block-zero-top block-zero-bottom\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-68516acba796f\" class=\"block-wysiwyg\">\n            <ul>\n<li><strong>A REMS is required<\/strong> by the FDA to ensure that the benefits of therapy outweigh the risks<\/li>\n<li><strong>The goal of the PALYNZIQ<sup>\u00ae<\/sup> (pegvaliase-pqpz) Injection REMS program<\/strong> is to mitigate the risk of anaphylaxis<sup>1<\/sup><\/li>\n<\/ul>\n    <\/div>\n\n<div id=\"acf-block-68516acba7b53\" class=\"block cards cards-2-col\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"cards-title\">\n\t\t\t    \t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"cards-wrapper\">\n\t\t\t    \n<div id=\"acf-block-68516acba8098\" class=\"card card-fixed-button\" data-muted-autoplay=\"false\">\n    \t    \n\n                    <img decoding=\"async\" class=\"card-image\" src=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-content\/uploads\/sites\/3\/2025\/06\/stethoscope2.png?v=0.117\" alt=\"\" \/>        \n\t    <div class=\"card-content\">\n                            <h4>Enroll yourself\n<\/h4>\n        \n                                                                                                            <ul>\n<li>Read the full Prescribing Information for PALYNZIQ<\/li>\n<li>Read the REMS Prescriber Guide<\/li>\n<li>Read the REMS Program Overview<\/li>\n<li>Complete the REMS Prescriber Knowledge Assessment<\/li>\n<li>Sign the REMS Prescriber Enrollment Form<\/li>\n<\/ul>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-text button-arrow\" href=\"https:\/\/www.palynziqrems.com\/#Main\" target=\"_blank\">Enroll now<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\n<div id=\"acf-block-68516acba8110\" class=\"card card-fixed-button\" data-muted-autoplay=\"false\">\n    \t    \n\n                    <img decoding=\"async\" class=\"card-image\" src=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-content\/uploads\/sites\/3\/2025\/06\/REMS-PAGE-ICONS_checklist.png?v=0.117\" alt=\"\" \/>        \n\t    <div class=\"card-content\">\n                            <h4>Enroll each patient\n<\/h4>\n        \n                                                                                                            <ul>\n<li>Counsel your patient on the risks associated with PALYNZIQ, including the risk of anaphylaxis and the need for autoinjectable epinephrine\n<ul>\n<li>Prescribe autoinjectable epinephrine, and instruct patients on how to use it and to carry it with them at all times<\/li>\n<\/ul>\n<\/li>\n<li>Review the following with your patient:\n<ul>\n<li>REMS Patient Guide<\/li>\n<li>REMS Wallet Card<\/li>\n<li>REMS Safety Video<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-text button-arrow\" href=\"https:\/\/www.palynziqrems.com\" target=\"_blank\">Click here to view REMS resources<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n        <\/div>\n    <\/div>\n        <\/div>\n\n<div id=\"acf-block-68516ec105681\" class=\"block wrapped-content bg-band block-zero-top block-zero-bottom\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-68516ec105801\" class=\"block-wysiwyg\">\n            <p>Visit <a href=\"https:\/\/www.palynziqrems.com\/#Main\" target=\"_blank\" rel=\"noopener\">PALYNZIQREMS.com<\/a> or submit signed completed forms by fax or mail to PALYNZIQ REMS:<\/p>\n<p><strong>Phone:<\/strong> 1-855-758-REMS<br \/>\n(1-855-758-7367)<br \/>\n<strong>Fax:<\/strong> 1-866-713-8421<br \/>\n<strong>PALYNZIQ REMS<br \/>\n200 Pinecrest Plaza<br \/>\nMorgantown,<br \/>\n<\/strong><strong>WV 26505<\/strong><\/p>\n<p><a class=\"button button-arrow\" href=\"https:\/\/www.palynziqrems.com\/#Main\" target=\"_blank\" rel=\"noopener\">Visit PALYNZIQREMS.com to enroll<\/a><\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n        <\/div>\n\n<div id=\"acf-block-686fb6253d167\" class=\"block wrapped-content bg-band bg-band-primary block-zero-top\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-686fb6253d2cc\" class=\"block-wysiwyg references\">\n            <p><small><strong>Reference: 1.<\/strong> PALYNZIQ [package insert]. Novato, CA: BioMarin Pharmaceutical Inc; 2025.<\/small><\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n        <\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-7224","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>BioMarin PALYNZIQ\u00ae | REMS Program Enrollment<\/title>\n<meta name=\"description\" content=\"Get certified to prescribe PALYNZIQ\u00ae through the REMS program.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BioMarin PALYNZIQ\u00ae | REMS Program Enrollment\" \/>\n<meta property=\"og:description\" content=\"Get certified to prescribe PALYNZIQ\u00ae through the REMS program.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/\" \/>\n<meta property=\"og:site_name\" content=\"BioMarin Palynziq HCP EN-US\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-17T19:32:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-content\/uploads\/sites\/3\/2023\/03\/palynziq-cover.jpg?v=0.117\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"675\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/\",\"url\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/\",\"name\":\"BioMarin PALYNZIQ\u00ae | REMS Program Enrollment\",\"isPartOf\":{\"@id\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/#website\"},\"datePublished\":\"2025-06-17T13:01:57+00:00\",\"dateModified\":\"2025-11-17T19:32:34+00:00\",\"description\":\"Get certified to prescribe PALYNZIQ\u00ae through the REMS program.\",\"breadcrumb\":{\"@id\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"PALYNZIQ REMs\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/#website\",\"url\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/\",\"name\":\"BioMarin Palynziq HCP EN-US\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"BioMarin PALYNZIQ\u00ae | REMS Program Enrollment","description":"Get certified to prescribe PALYNZIQ\u00ae through the REMS program.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/","og_locale":"en_US","og_type":"article","og_title":"BioMarin PALYNZIQ\u00ae | REMS Program Enrollment","og_description":"Get certified to prescribe PALYNZIQ\u00ae through the REMS program.","og_url":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/","og_site_name":"BioMarin Palynziq HCP EN-US","article_modified_time":"2025-11-17T19:32:34+00:00","og_image":[{"width":1200,"height":675,"url":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-content\/uploads\/sites\/3\/2023\/03\/palynziq-cover.jpg?v=0.117","type":"image\/jpeg"}],"twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/","url":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/","name":"BioMarin PALYNZIQ\u00ae | REMS Program Enrollment","isPartOf":{"@id":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/#website"},"datePublished":"2025-06-17T13:01:57+00:00","dateModified":"2025-11-17T19:32:34+00:00","description":"Get certified to prescribe PALYNZIQ\u00ae through the REMS program.","breadcrumb":{"@id":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/resources-rems\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/"},{"@type":"ListItem","position":2,"name":"PALYNZIQ REMs"}]},{"@type":"WebSite","@id":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/#website","url":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/","name":"BioMarin Palynziq HCP EN-US","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-json\/wp\/v2\/pages\/7224","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-json\/wp\/v2\/comments?post=7224"}],"version-history":[{"count":25,"href":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-json\/wp\/v2\/pages\/7224\/revisions"}],"predecessor-version":[{"id":7822,"href":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-json\/wp\/v2\/pages\/7224\/revisions\/7822"}],"wp:attachment":[{"href":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-json\/wp\/v2\/media?parent=7224"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}