{"id":3555,"date":"2022-09-05T19:35:44","date_gmt":"2022-09-05T19:35:44","guid":{"rendered":"https:\/\/palynziqhcp-dev-001.azurewebsites.net\/en-us\/palynziq\/?page_id=3555"},"modified":"2024-06-12T13:39:54","modified_gmt":"2024-06-12T13:39:54","slug":"mechanism-of-action-and-efficacy-video","status":"publish","type":"page","link":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/mechanism-of-action-and-efficacy-video\/","title":{"rendered":"Mechanism of Action and Efficacy &#8211; Video"},"content":{"rendered":"<div id=\"acf-block-63f659fd2e5fa\" class=\"block split-content content-align-top bottom-border\" data-muted-autoplay=\"false\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t                                                                <div class=\"content-block\">\n                                                                                                                                                                                                                                                <div class=\"video-poster\">\n\t\t\t                            <a class=\"modal-video permitted\" href=\"https:\/\/player.vimeo.com\/video\/664754228\" style=\"background-image: url(https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-content\/uploads\/sites\/3\/2023\/03\/videopage-bg-sq_opt.png?v=0.77);\">Play<\/a>\n\t\t                            <\/div>\n\t\t                                                                            <\/div>\n                    \n                                            <div class=\"content-block\">\n                                                                                                <h5>PALYNZIQ<sup>\u00ae<\/sup>\u00a0(pegvaliase-pqpz) Injection &#8211; A Phe-lowering Enzyme Therapy for Adults With PKU<\/h5>\n<p><small>For Healthcare Professionals<\/small><\/p>\n<p><strong>Mechanism of Action and Efficacy<\/strong><\/p>\n<p>Dr. Barbara Burton and Heather Bausell, RD, LDN, from Ann &amp; Robert H. Lurie Children\u2019s Hospital of Chicago discuss PALYNZIQ\u2019s mechanism of action and efficacy data associated with significant blood Phe reduction to reach meaningful blood Phe targets.<\/p>\n<p><strong>Indication<\/strong><\/p>\n<p>PALYNZIQ is a phenylalanine (Phe)-metabolizing enzyme indicated to reduce blood Phe concentrations in adult patients with phenylketonuria who have uncontrolled blood Phe concentrations greater than 600 micromol\/L on existing management.<br \/>\n<strong><br \/>\nPlease see full <a href=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-content\/uploads\/sites\/3\/2022\/08\/prescribinginformation.pdf?v=0.5\" target=\"_blank\" rel=\"noopener\">Prescribing Information<\/a>, with Boxed Warning for risk of anaphylaxis, and Medication Guide, <a href=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-content\/uploads\/sites\/3\/2022\/08\/PALYNZIQ-medication-guide.pdf?v=0.5\" target=\"_blank\" rel=\"noopener\">here<\/a>.<\/strong><\/p>\n<p><a href=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/safety-profile-video\/\">Next Video<\/a><\/p>\n                                                                                    <\/div>\n                                                \t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-63f659fd2e63d\" class=\"block wrapped-content\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                        <\/div>\n    <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mechanism of Action Video | Palynziq HCP<\/title>\n<meta name=\"description\" content=\"View a PALYNZIQ virtual education program discussing: Mechanism of action; 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