{"id":3525,"date":"2022-09-05T19:21:03","date_gmt":"2022-09-05T19:21:03","guid":{"rendered":"https:\/\/palynziqhcp-dev-001.azurewebsites.net\/en-us\/palynziq\/?page_id=3525"},"modified":"2024-06-12T13:47:52","modified_gmt":"2024-06-12T13:47:52","slug":"safety-profile-video","status":"publish","type":"page","link":"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/safety-profile-video\/","title":{"rendered":"Safety Profile &#8211; Video"},"content":{"rendered":"<div id=\"acf-block-63f6568552e4b\" class=\"block split-content equal-bias content-align-top bottom-border\" data-muted-autoplay=\"false\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t                                                                <div class=\"content-block first-block\">\n                                                                                                                                                                                                                                                <div class=\"video-poster\">\n\t\t\t                            <a class=\"modal-video permitted\" href=\"https:\/\/player.vimeo.com\/video\/664755062\" style=\"background-image: url(https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-content\/uploads\/sites\/3\/2023\/03\/Screenshot-2022-08-10-at-14.25.46_opt-1500x838.jpg);\">Play<\/a>\n\t\t                            <\/div>\n\t\t                                                                            <\/div>\n                    \n                                            <div class=\"content-block second-block\">\n                                                                                                <h5>PALYNZIQ\u00ae (pegvaliase-pqpz) Injection &#8211; A Phe-lowering Enzyme Therapy for Adults With PKU<\/h5>\n<p><small>For Healthcare Professionals<\/small><\/p>\n<p><strong>Safety<\/strong><\/p>\n<p>Dr. Barbara Burton and Heather Bausell, RD, LDN, provide a detailed overview of PALYNZIQ\u2019s safety profile, including data showing how the rates of the 3 most common adverse reactions decrease from induction\/titration to maintenance, regardless of the specific maintenance dose (20 mg, 40 mg, or 60 mg).<\/p>\n<p><strong>Indication<\/strong><\/p>\n<p>PALYNZIQ is a phenylalanine (Phe)-metabolizing enzyme indicated to reduce blood Phe concentrations in adult patients with phenylketonuria who have uncontrolled blood Phe concentrations greater than 600 micromol\/L on existing management.<\/p>\n<p><strong>Please see full <a href=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/wp-content\/uploads\/sites\/3\/2022\/08\/prescribinginformation.pdf?v=0.5\" target=\"_blank\" rel=\"noopener\">Prescribing Information<\/a>, with Boxed Warning for risk of anaphylaxis, and Medication Guide, <a href=\"#important-safety-information\">here.<\/a><\/strong><\/p>\n<p><a href=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/dosing-and-administration-video\/\">Next Video<\/a><\/p>\n                                                                                    <\/div>\n                                                \t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-63f6568552eca\" class=\"block wrapped-content\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                        <\/div>\n    <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-3525","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Safety Profile Video | Palynziq HCP<\/title>\n<meta name=\"description\" content=\"Listen to PKU experts review PALYNZIQ&#039;s safety and efficacy, and discuss the clinical considerations that their team evaluates when administering PALYNZIQ.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/safety-profile-video\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Safety Profile Video | Palynziq HCP\" \/>\n<meta property=\"og:description\" content=\"Listen to PKU experts review PALYNZIQ&#039;s safety and efficacy, and discuss the clinical considerations that their team evaluates when administering PALYNZIQ.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/safety-profile-video\/\" \/>\n<meta property=\"og:site_name\" content=\"BioMarin Palynziq HCP EN-US\" \/>\n<meta property=\"article:modified_time\" content=\"2024-06-12T13:47:52+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/safety-profile-video\/\",\"url\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/safety-profile-video\/\",\"name\":\"Safety Profile Video | Palynziq HCP\",\"isPartOf\":{\"@id\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/#website\"},\"datePublished\":\"2022-09-05T19:21:03+00:00\",\"dateModified\":\"2024-06-12T13:47:52+00:00\",\"description\":\"Listen to PKU experts review PALYNZIQ's safety and efficacy, and discuss the clinical considerations that their team evaluates when administering PALYNZIQ.\",\"breadcrumb\":{\"@id\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/safety-profile-video\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/safety-profile-video\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/safety-profile-video\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/hcp.biomarin.com\/en-us\/palynziq\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Safety Profile &#8211; 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