{"id":7,"date":"2022-10-12T12:00:36","date_gmt":"2022-10-12T12:00:36","guid":{"rendered":"https:\/\/brineurahcp-dev-001.azurewebsites.net\/en-us\/brineura\/?page_id=7"},"modified":"2026-03-11T12:48:40","modified_gmt":"2026-03-11T12:48:40","slug":"home","status":"publish","type":"page","link":"https:\/\/hcp.biomarin.com\/en-us\/brineura\/","title":{"rendered":"Home"},"content":{"rendered":"
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\n\t\t\t \t\t\t\t To slow the loss of ambulation in pediatric patients with neuronal ceroid lipofuscinosis type 2 (CLN2 disease)<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t

Helping your patients take a step forward\n<\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t

Brineura\u00ae (cerliponase alfa) helps replace deficient tripeptidyl peptidase 1 (TPP1) enzyme in patients with CLN2 disease, a common form of Batten disease.<\/p>\n\t\t\t\t\t\t\t\t\n

\n \t\t\t\t REGISTER NOW<\/a>\t\t\t\t <\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n

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How does
\nBrineura work?\n<\/h4>\n \n

Brineura, an enzyme replacement, is the first and only treatment addressing the underlying cause of CLN2 disease.<\/p>\n \n <\/div>\n

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Mechanism of Action<\/a><\/p>\n <\/div>\n<\/div>\n\n

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How is Brineura
\nadministered?\n<\/h4>\n \n

Brineura is administered into the cerebrospinal fluid via intraventricular infusion.<\/p>\n \n <\/div>\n

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Dosing & Admin Guide<\/a><\/p>\n <\/div>\n<\/div>\n\n

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How can I stay informed
\nabout Brineura?\n<\/h4>\n \n

Stay current on the latest news about CLN2 disease and Brineura by signing up to receive email updates from BioMarin.<\/p>\n \n <\/div>\n

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Register Today<\/a><\/p>\n <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-7","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nHome - BioMarin Brineura HCP EN-US<\/title>\n<meta name=\"description\" content=\"Brineura\u00ae (cerliponase alfa) helps replace deficient tripeptidyl peptidase 1 (TPP1) enzyme in patients with CLN2 disease, a common form of Batten disease.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hcp.biomarin.com\/en-us\/brineura\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Home\" \/>\n<meta property=\"og:description\" content=\"Brineura\u00ae (cerliponase alfa) helps replace deficient tripeptidyl peptidase 1 (TPP1) enzyme in patients with CLN2 disease, a common form of Batten disease.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/hcp.biomarin.com\/en-us\/brineura\/\" \/>\n<meta property=\"og:site_name\" content=\"BioMarin Brineura HCP EN-US\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-11T12:48:40+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/brineura\\\/\",\"url\":\"https:\\\/\\\/hcp.biomarin.com\\\/en-us\\\/brineura\\\/\",\"name\":\"Home - 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