{"id":2153,"date":"2023-05-09T14:02:51","date_gmt":"2023-05-09T14:02:51","guid":{"rendered":"https:\/\/hcp.biomarin.com\/en-us\/achondroplasia\/?page_id=2153"},"modified":"2025-05-14T12:47:07","modified_gmt":"2025-05-14T12:47:07","slug":"flowchart","status":"publish","type":"page","link":"https:\/\/hcp.biomarin.com\/en-us\/achondroplasia\/flowchart\/","title":{"rendered":"Flowchart"},"content":{"rendered":"<div class=\"wrapper\">\n  <div class=\"inner-wrapper\">\n    <div class=\"gmaf-wrapper\">\n      <div id=\"gmaf-overlay\"><\/div>\n      <div class=\"header-bottom\">\n        <select name=\"topic\" id=\"topic-dropdown\">\n          <option value=\"\" disabled>Select Topic<\/option>\n          <option value=\"foramen\">Foramen Magnum Stenosis<\/option>\n          <option value=\"otitis\">Otitis Media<\/option>\n          <option value=\"spinal\">Spinal Stenosis<\/option>\n          <option value=\"kyphosis\">Kyphosis Thoracic<\/option>\n          <option value=\"genu\">Genu Varum<\/option>\n          <option value=\"growth\">Growth and Development<\/option>\n        <\/select>\n        <h2 id=\"gmaf-subhead\" class=\"gmaf-hidden\">This tool contains summarized content and is meant to be reviewed alongside the International Consensus Statement, which can be accessed <a href=\"https:\/\/eprintserver2.medengine.com\/cop23un012230\/\" target=\"_blank\" rel=\"noreferrer\">here<\/a>.<\/h2>\n      <\/div>\n\n      <!-- Content Pages -->\n      <div class=\"gmaf-page\" data-page-id=\"intro\">\n\n        <div class=\"gmaf-flex\">\n          <div class=\"text-side\">\n            <h1>An interactive guide to managing complications in achondroplasia<\/h1>\n            <p>This interactive tool is based on guidance adapted from the International Consensus Statement\u2014a\n              publication developed by\n              55 specialists from 16 different countries to help standardize care for patients with achondroplasia, with\n              sponsorship from BioMarin Pharmaceutical Inc.<\/p>\n            <p>Discover helpful guidance centering around diagnosis, multidisciplinary treatment, and lifelong care for\n              individuals with achondroplasia, across each stage of life.<\/p>\n            <p>Review this tool in conjunction with the <a href=\"https:\/\/www.nature.com\/articles\/s41574-021-00595-x\" target=\"_blank\" class=\"gmaf-bold gmaf-underline\">International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia<img decoding=\"async\" src=\"https:\/\/hcp.biomarin.com\/en-us\/achondroplasia\/wp-content\/themes\/biomarin-ach-dse\/img\/components\/flowchart\/global\/caret-blue.svg\" alt=\"arrow icon\"><\/a>\n            <\/p>\n            <p class=\"\">The initial meeting of experts was sponsored by BioMarin Pharmaceuticals Inc., who also provided logistic assistance. The International Consensus Statement publication was funded by BioMarin, but developed independently. The publication should be read in its entirety. This website does not provide medical advice and does not replace the need for independent research, medical judgment, or review and analysis of additional resources.<\/p>\n            <p class=\"disclaimer gmaf-desktop\">This interactive guide is intended for healthcare professionals only.<\/p>\n            <p class=\"disclaimer gmaf-desktop\">Graphics were developed by BioMarin based on the International Consensus\n              Statement.<\/p>\n          <\/div>\n\n          <div class=\"interactive-side\">\n            <svg class=\"gmaf-desktop\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" width=\"100%\" viewBox=\"0 0 584 713\">\n              <defs>\n                <style>\n                  .a {\n                    fill: none;\n                  }\n\n                  .b {\n                    fill: #fff;\n                  }\n\n                  .c,\n                  .h {\n                    fill: #2f5197;\n                  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transform=\"translate(777.364 -69.422)\" \/>\n                  <text class=\"h\" transform=\"translate(886 664.614)\">\n                    <tspan x=\"-37.77\" y=\"0\">Kyphosis<\/tspan>\n                    <tspan x=\"-34.77\" y=\"24\">Thoracic<\/tspan>\n                  <\/text>\n                  <path class=\"c\" d=\"M.111,7.263l.626.625a.38.38,0,0,0,.537,0L7,2.18l5.725,5.708a.38.38,0,0,0,.537,0l.626-.625a.379.379,0,0,0,0-.537L7.269.111a.38.38,0,0,0-.537,0L.111,6.726A.379.379,0,0,0,.111,7.263Z\" transform=\"translate(945 676.614) rotate(90)\" \/>\n                <\/g>\n                <g class=\"hotspot\" data-comp-id=\"growth\" transform=\"translate(150.285 -82.893)\">\n                  <g transform=\"translate(997 809.649)\">\n                    <text class=\"h\" transform=\"translate(76 20)\">\n                      <tspan x=\"-35.11\" y=\"0\">Growth <\/tspan>\n                      <tspan x=\"-75.97\" y=\"24\">and Development<\/tspan>\n                    <\/text>\n         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d=\"M24.9,5.838,28.519,8.6,18.67,21.526l-4.31-3.284L0,37.091l1.077.82,13.54-17.772,4.31,3.284L30.416,8.342,27.608,6.2l10.107-4.09L36.456,12.943,33.647,10.8,19.7,29.116l-4.308-3.282L8.43,34.967l1.077.82,6.137-8.056,4.308,3.282L33.9,12.7l3.622,2.76L39.323,0Z\" transform=\"translate(1055.839 750.51)\" \/>\n                  <path class=\"g\" d=\"M39.917-.779l-2,17.17L34,13.4,20.047,31.714l-4.308-3.282L9.6,36.488,7.73,35.062l7.564-9.928L19.6,28.415,33.552,10.1l2.508,1.911,1.06-9.122L28.609,6.336l2.508,1.911-12.1,15.877-4.31-3.284L1.172,38.612-.7,37.186,14.265,17.542l4.31,3.284L27.818,8.693,23.9,5.7Zm-2.786,15.31L38.729.78,25.9,5.973,29.22,8.5,18.765,22.227l-4.31-3.284L.7,37l.281.214,13.54-17.772,4.31,3.284L29.715,8.436,26.606,6.068l11.7-4.736L36.851,13.872,33.742,11.5,19.79,29.817l-4.308-3.282L9.131,34.872l.281.214L15.55,27.03l4.308,3.282L33.809,12Z\" transform=\"translate(1055.839 750.51)\" \/>\n                <\/g>\n              <\/g>\n              <\/g>\n            <\/svg>\n            <img decoding=\"async\" class=\"gmaf-mobile\" src=\"https:\/\/hcp.biomarin.com\/en-us\/achondroplasia\/wp-content\/themes\/biomarin-ach-dse\/img\/components\/flowchart\/body-chart-mobile.svg\" alt=\"Side profiled, blue silhouette illustration of a child with achondroplasia\" \/>\n            <div class=\"hotspot-container gmaf-mobile\">\n              <div class=\"inner\">\n                <div class=\"hotspot\" data-comp-id=\"otitis\"><\/div>\n                <div class=\"hotspot\" data-comp-id=\"foramen\"><\/div>\n                <div class=\"hotspot\" data-comp-id=\"spinal\"><\/div>\n                <div class=\"hotspot\" data-comp-id=\"kyphosis\"><\/div>\n                <div class=\"hotspot\" data-comp-id=\"genu\"><\/div>\n                <div class=\"hotspot\" data-comp-id=\"growth\"><\/div>\n              <\/div>\n            <\/div>\n\n          <\/div>\n        <\/div>\n        <p class=\"disclaimer gmaf-mobile\">This interactive guide is intended for healthcare professionals only. Graphics\n          were\n          developed by BioMarin based on the International Consensus Statement.<\/p>\n      <\/div>\n      <div class=\"gmaf-page\" data-page-id=\"flow\">\n        <div id=\"question-box\">\n          <p id=\"question-ref-wrapper\"><span id=\"question-ref-text\"><\/span><\/p>\n\n          <img decoding=\"async\" class=\"gmaf-icon\" src=\"\" alt=\"\" \/>\n          <p id=\"question-text\"><\/p>\n\n          <div class=\"gmaf-flex options-container\">\n            <div class=\"option\">\n              <p id=\"option-text\"><\/p>\n            <\/div>\n            <div class=\"option\">\n              <p id=\"option-text\"><\/p>\n            <\/div>\n          <\/div>\n\n        <\/div>\n\n        <div id=\"guide-box\">\n          <p id=\"guide-ref-wrapper\"><span id=\"guide-ref-text\"><\/span><\/p>\n\n          <img decoding=\"async\" class=\"gmaf-icon\" src=\"https:\/\/hcp.biomarin.com\/en-us\/achondroplasia\/wp-content\/themes\/biomarin-ach-dse\/img\/components\/flowchart\/global\/guidance.svg\" alt=\"Graphic of a clipboard with a checklist\" \/>\n          <h2>General Guidance<\/h2>\n\n          <div class=\"notes\"><\/div>\n\n          <div class=\"gmaf-flex\">\n            <div id=\"finish\">\n              <p class=\"gmaf-all-caps\">Learn More<\/p>\n            <\/div>\n\n            <div id=\"restart-1\">\n              <p class=\"gmaf-all-caps\">Select New Topic<\/p>\n            <\/div>\n          <\/div>\n\n          <div class=\"gmaf-button mir-button\" id=\"medical-info-req\">\n            <p><a href=\"https:\/\/www.biomarin.com\/contact-medinfo\/\" target=\"_blank\">Medical Information Request<\/a><\/p>\n          <\/div>\n\n          <hr>\n\n          <div class=\"gmaf-ref-container\">\n            <p><\/p>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div class=\"gmaf-page\" data-page-id=\"exit\">\n        <div class=\"gmaf-flex\">\n          <div class=\"white-side\">\n            <h1>Thank you for participating!<\/h1>\n            <p>Continue expanding your knowledge about achondroplasia and <br class=\"gmaf-desktop\" \/>help current or\n              future patients<\/p>\n\n            <a href=\"https:\/\/www.nature.com\/articles\/s41574-021-00595-x\" target=\"_blank\" class=\"ext-arrow gmaf-underline mobile-two-line\">Go to the full International <br class=\"gmaf-mobile\" \/>Consensus Statement<\/a>\n            <a href=\"https:\/\/hcp.achondroplasia.com\/stay-updated\" target=\"_blank\" class=\"ext-arrow gmaf-underline\">Sign\n              up to stay informed<\/a>\n\n                      <\/div>\n        <\/div>\n\n        <div class=\"restart-div\">\n          <h1>Continue exploring complications to optimize care for patients with achondroplasia<\/h1>\n\n          <div class=\"gmaf-button\" id=\"restart-2\">\n            <p class=\"\">Select New Topic<\/p>\n            <img decoding=\"async\" src=\"https:\/\/hcp.biomarin.com\/en-us\/achondroplasia\/wp-content\/themes\/biomarin-ach-dse\/img\/components\/flowchart\/global\/caret-blue.svg\" alt=\"arrow icon\" \/>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div class=\"footer-disclaimer gmaf-hidden\" data-page-id=\"intro\">\n        <p class=\"disclaimer\">The initial meeting of experts was sponsored by BioMarin Pharmaceuticals Inc., who also provided logistic assistance. The International Consensus Statement publication was funded by BioMarin, but developed independently. The publication should be read in its entirety. This website does not provide medical advice and does not replace the need for independent research, medical judgment, or review and analysis of additional resources.<\/p>\n        <p class=\"disclaimer\"><a href=\"https:\/\/www.nature.com\/articles\/s41574-021-00595-x\" target=\"_blank\">International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia<\/a><\/p>\n      <\/div>\n      <hr>\n      <div class=\"gmaf-footer-global-reference\">\n        <p><span class=\"gmaf-bold\">Reference:<\/span> Savarirayan R, Ireland P, Irving M, et al. International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia. <em>Nat Rev Endocrinol<\/em>. 2022;18(3):173-189.<\/p>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-2153","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Flowchart - BioMarin ACH DSE HCP EN-US<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hcp.biomarin.com\/en-us\/achondroplasia\/flowchart\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Flowchart - 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