{"id":12,"date":"2022-11-15T14:05:11","date_gmt":"2022-11-15T14:05:11","guid":{"rendered":"https:\/\/mpsdsehcp-dev-001.azurewebsites.net\/en-gb\/mucopolysaccharidosis-mps\/?page_id=12"},"modified":"2023-12-04T09:12:41","modified_gmt":"2023-12-04T09:12:41","slug":"home","status":"publish","type":"page","link":"https:\/\/hcp.biomarin.com\/en-gb\/mps\/","title":{"rendered":"Home"},"content":{"rendered":"
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Recognise the signs, identify the disease\n<\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t

“MPSs are multisystemic, progressive, treatable diseases, so diagnosis should be made as early as possible.”<\/p>\n

Dr. Mireia del Toro <\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n

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Early recognition hinges on early suspicion\n<\/h3>\n

In many genetic conditions, diagnostic delay is common due to lack of clinical suspicion.<\/p>\n

What is MPS?<\/a><\/p>\n <\/div>\n<\/div>\n\n

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Discover the signs and symptoms of MPS\n<\/h3>\n

Presentation and disease progression are unpredictable, multisystemic and variable across and within MPS disorders, making diagnosis challenging.1<\/sup><\/p>\n

Take a closer look at the signs and symptoms <\/a><\/p>\n <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n

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Discover the pathology behind the presentation<\/h2>\n

Watch how MPS affects patients from the inside out. As an example, this video illustrates the mechanism of disease for Morquio A (MPS IVA).<\/p>\n

Learn more <\/a><\/p>\n <\/div>\n \t\t<\/div>\n\t<\/div>\n<\/div>\n\n

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Register for access\n<\/h2>\n\t\t\t\t\t\t \t\t\t\t\t\t \t\t\t\t\t\t

Discover more online at MPSmeetings.com. Unlock exclusive content, listen to expert-led podcasts, watch on-demand webinars and much more.<\/p>\n\t\t\t\t\t\t \t\t\t\t\t <\/div>\n\t\t\t\t\t

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Register Now<\/a><\/p>\n <\/div>\n\t\t\t\t\t <\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n

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Is there a rare genetic disease hiding in your department?<\/h2>\n

Often mischaracterised as either purely a childhood disorder or a musculoskeletal disease, MPS might not be as uncommon as you think.<\/p>\n

Consider MPS<\/a><\/p>\n <\/div>\n \n

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Optimise outcomes – change the clinical course for your patients<\/h2>\n

MPS disorders are complex, multisystemic conditions whose unique risks and life\u2013altering complications require careful, coordinated care from a multidisciplinary team of specialists.1-5<\/sup> The emergence of specific therapies for some MPS disorders has elevated the critical nature of early intervention and diagnosis as key components of optimal, long-term outcomes.1,2,3,6,7<\/sup><\/p>\n

Manage your patients with MPS <\/a><\/p>\n <\/div>\n \n

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References:\n<\/h4>\n\t\t\t\t\t\t
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  1. Lehman TJA et al. Diagnosis of the mucopolysaccharidoses. Rheumatology. 2011;50(suppl 5):v41\u2013v48\n<\/span><\/li>\n
  2. Muenzer J, Wraith JE, Clarke LA, International Consensus Panel on the Management and Treatment of Mucopolysaccharidosis I. Mucopolysaccharidosis I: management and treatment guidelines. Pediatrics. 2009;123(1):19\u201329. doi:10.1542\/peds.2008-0416.\n<\/span><\/li>\n
  3. Muenzer J, Beck M, Eng CM, et al.Genet Med. 2011;13(2):95\u2013101. doi:10.1097\/GIM.0b013e3181fea459.\n<\/span><\/li>\n
  4. Klitzner TS, Rabbitt LA, Chang RKR. Benefits of care coordination for children with complex disease: a pilot medical home project in a resident teaching clinic. J Pediatr. 2010;156(6):1006\u20131010. doi:10.1016\/j.jpeds.2009.12.012.\n<\/span><\/li>\n
  5. Mosquera RA, Avritscher EBC, Samuels CL, et al. Effect of an enhanced medical home on serious illness and cost of care among high-risk children with chronic illness: a randomized clinical trial. JAMA. 2014;312(24):2640\u20132648. doi:10.1001\/jama.2014.16419. \n<\/span><\/li>\n
  6. Clarke LA. Pathogenesis of skeletal and connective tissue involvement in the mucopolysaccharidoses: glycosaminoglycan storage is merely the instigator. Rheumatology (Oxford). 2011;50(suppl 5):v13\u201318. doi:10.1093\/rheumatology\/ker395.\n<\/span><\/li>\n
  7. Morishita K, Petty RE. Musculoskeletal manifestations of mucopolysaccharidoses. Rheumatology. 2011;50(suppl 5):v19\u2013v25. doi:10.1093\/rheumatology\/ker397.\n<\/span><\/li>\n <\/ol>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-12","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nHome - BioMarin MPS DSE HCP EN-GB<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hcp.biomarin.com\/en-gb\/mps\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Home - BioMarin MPS DSE HCP EN-GB\" \/>\n<meta property=\"og:url\" content=\"https:\/\/hcp.biomarin.com\/en-gb\/mps\/\" \/>\n<meta property=\"og:site_name\" content=\"BioMarin MPS DSE HCP EN-GB\" \/>\n<meta property=\"article:modified_time\" content=\"2023-12-04T09:12:41+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/hcp.biomarin.com\/en-gb\/mps\/\",\"url\":\"https:\/\/hcp.biomarin.com\/en-gb\/mps\/\",\"name\":\"Home - 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