{"id":19,"date":"2022-11-03T18:34:19","date_gmt":"2022-11-03T18:34:19","guid":{"rendered":"https:\/\/achdsehcp-dev-001.azurewebsites.net\/en-us\/achondroplasia\/?page_id=19"},"modified":"2024-02-26T11:41:54","modified_gmt":"2024-02-26T11:41:54","slug":"impact","status":"publish","type":"page","link":"https:\/\/hcp.biomarin.com\/en-gb\/achondroplasia\/impact\/","title":{"rendered":"Impact"},"content":{"rendered":"
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Achondroplasia complications\n<\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t

Although complications may resolve over time, anticipatory management may help mitigate serious, otherwise unexpected health <\/span><\/span>consequences. Explore the possible implications of achondroplasia below.<\/span><\/span>\u200b<\/span><\/p>\n\t\t\t\t\t\t\t\t\n

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Familiarise yourself with the affected systems<\/h2>\n

Short stature is a measurable characteristic of achondroplasia, and complications can develop as a result of impaired bone growth. This includes broader health implications such as delayed motor development, chronic otitis media, and sleep disordered breathing in childhood, and spinal stenosis, chronic pain, and mobility issues in adults, just to name a few.<\/p>\n <\/div>\n\n

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While there is no impact on cognitive functioning, children with achondroplasia are faced with musculoskeletal, otolaryngological, neurological<\/strong> and spinal<\/strong> complications, some of which may require surgery to be corrected.1-3<\/sup><\/p>\n <\/div>\n <\/div>\n <\/div>\n<\/div>\n\n

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Make sure you\u2019re prepared\n<\/h2>\n\t\t\t\t\t\t \t\t\t\t\t\t \t\t\t\t\t\t

The most effective management of achondroplasia means anticipating specific complications at every stage of development.<\/p>\n\t\t\t\t\t\t \t\t\t\t\t <\/div>\n\t\t\t\t\t

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Common achondroplasia complications that may result in an individual’s lifetime<\/h2>\n

Keep these complications top-of-mind to help give families a perspective of what to watch out for2-9<\/sup><\/p>\n <\/div>\n <\/div>\n <\/div>\n<\/div>\n\n

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Sleep disordered breathing\n<\/h4>\n \n

Affects >50% of people with achondroplasia<\/p>\n <\/div>\n<\/div>\n\n

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Genu varum (tibial bowing)\n<\/h4>\n \n

Can affect walking and running<\/p>\n <\/div>\n<\/div>\n\n

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Symptomatic spinal stenosis\n<\/h4>\n \n

Can lead to leg weakness, incontinence,\u00a0and chronic pain<\/p>\n <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n

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Chronic pain\n<\/h4>\n \n

Can result in loss of mobility<\/p>\n <\/div>\n<\/div>\n\n

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Lumbar hyperlordosis\n<\/h4>\n \n

May require physical therapy<\/p>\n <\/div>\n<\/div>\n\n

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Otitis media\n<\/h4>\n \n

Affects up to 70% of children<\/p>\n <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n

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Dental issues\n<\/h4>\n \n

Crowded teeth and a narrow upper jaw may lead to a crossbite<\/p>\n <\/div>\n<\/div>\n\n

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Elbow stiffness\n<\/h4>\n \n

Limits range\u00a0of motion<\/p>\n <\/div>\n<\/div>\n\n

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Obesity\n<\/h4>\n \n

Can lead to high blood pressure or\u00a0heart\u00a0disease<\/p>\n <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n

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Achondroplasia complications over a lifetime<\/h2>\n

Although complications may resolve over time, anticipatory management may help mitigate serious, otherwise unexpected health consequences. Explore the below preparations that could be made to combat the effects of achondroplasia.<\/p>\n

Infants<\/h3>\n

Impaired bone growth affects the entire body, and its impact on the size and shape of the foramen magnum can lead to cervicomedullary compression. This can put infants at risk for sudden death, making regular monitoring, management, and timely referrals crucial for this stage.2,3,7,10-16<\/sup><\/p>\n

It is important to keep an eye on complications that can quickly\u2014and quietly\u2014progress.<\/strong><\/p>\n

Download the Complication Timeline Resource<\/a><\/p>\n <\/div>\n <\/div>\n <\/div>\n<\/div>\n\n

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